Ku-80 Monoclonal Antibody, 50ul Metabolic enzymes tool compounds Suppresses Src-dependent tyrosine phosphorylation and

Suppresses Src-dependent tyrosine phosphorylation and activation of PDPK1 and its downstream signaling

This kinase was shown to be responsible for the phosphorylation of retinoblastoma gene product (Rb)

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This protein binds to the serum response element (SRE) in the promoter region of target genes

Ku-80 Monoclonal Antibody, 50ul Metabolic enzymes tool compounds Suppresses Src-dependent tyrosine phosphorylation andThe protein encoded by this gene is the 80 kilodalton subunit of the Ku heterodimer protein which is also known as ATP dependant DNA helicase II or DNA repair protein XRCC5. Ku is the DNA binding component of the DNA dependent protein kinase, and it functions together with the DNA ligase IV XRCC4 complex in the repair of DNA double strand break by non homologous end joining and the completion of V(D)J recombination events. This gene functionally