KGP1 Polyclonal Antibody, 100ul Polyclonal Antibodies Mutations in CASP10 are associated

Mutations in CASP10 are associated with type IIA autoimmune lymphoproliferative syndrome

This protein is localized to the trans Golgi network

Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase is a membrane-associated kinase that negatively regulates the G2/M transition of the cell cycle by phosphorylating and inactivating cyclin-dependent kinase 1

Several alternatively spliced transcript variants have been identified from this gene

KGP1 Polyclonal Antibody, 100ul Polyclonal Antibodies Mutations in CASP10 are associatedMammals have three different isoforms of cyclic GMP dependent protein kinase (Ialpha, Ibeta, and II). These PRKG isoforms act as key mediators of the nitric oxide cGMP signaling pathway and are important components of many signal transduction processes in diverse cell types. This PRKG1 gene on human chromosome 10 encodes the soluble Ialpha and Ibeta isoforms of PRKG by alternative transcript splicing. A separate gene on human chromosome 4, PRKG2,