JIP-1(Phospho Thr103) Polyclonal Antibody, 50ul Stepper The protein encoded by this

The protein encoded by this gene is a putative tRNA methyltransferase found in the cytoplasm

mismatch repair system component encoded by PMS2 is a key component of the mismatch repair system that functions to correct DNA mismatches and small insertions and deletions that can occur during DNA replication and homologous recombination

associate with p34cdc2 and are essential components of the cell cycle regulatory machinery

It was previously thought that this gene mapped to 3q26 and that it was fused to the acute myeloid leukemia 1 (AML1) gene located at 21q22 in some therapy-related myelodysplastic syndrome patients with 3

JIP-1(Phospho Thr103) Polyclonal Antibody, 50ul Stepper The protein encoded by thisThis gene encodes a regulator of the pancreatic beta cell function. It is highly similar to JIP 1, a mouse protein known to be a regulator of c Jun amino terminal kinase (Mapk8). This protein has been shown to prevent MAPK8 mediated activation of transcription factors, and to decrease IL 1 beta and MAP kinase kinase 1 (MEKK1) induced apoptosis in pancreatic beta cells. This protein also functions as a DNA binding transactivator of the glucose