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MVK Polyclonal Antibody, 100ul Molecular Biology The expression of these transcripts

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MVK Polyclonal Antibody, 100ul Molecular Biology The expression of these transcriptsMVK encodes the peroxisomal enzyme mevalonate kinase. Mevalonate is a key intermediate, and mevalonate kinase a key early enzyme, in isoprenoid and sterol synthesis. Mevalonate kinase deficiency caused by mutation of MVK results in mevalonic aciduria, a disease characterized psychomotor retardation, failure to thrive, hepatosplenomegaly, anemia and recurrent febrile crises. Defects in this gene also cause hyperimmunoglobulinaemia D and periodic fever

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Description

The expression of these transcripts is restricted to the salivary gland among the human tissues examined

ADPGK catalyzes the ADP-dependent phosphorylation of glucose to glucose-6-phosphate and may play a role in glycolysis

The protein encoded by this gene is a serine proteinase that inhibits the activity of tissue-type plasminogen activator I

May be able to induce the degradation of filamin-A

MVK Polyclonal Antibody, 100ul Molecular Biology The expression of these transcriptsMVK encodes the peroxisomal enzyme mevalonate kinase. Mevalonate is a key intermediate, and mevalonate kinase a key early enzyme, in isoprenoid and sterol synthesis. Mevalonate kinase deficiency caused by mutation of MVK results in mevalonic aciduria, a disease characterized psychomotor retardation, failure to thrive, hepatosplenomegaly, anemia and recurrent febrile crises. Defects in this gene also cause hyperimmunoglobulinaemia D and periodic fever

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