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Keratin 8 Polyclonal Antibody, 20ul Dry Bath A mutation in the mouse

SKU: 23800350784

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Keratin 8 Polyclonal Antibody, 20ul Dry Bath A mutation in the mouseThis gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal

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Description

A mutation in the mouse ortholog of this gene results in homeotic| posterior-to-anterior transformations of the axial skeleton which are similar to the phenotype of mouse homeobox C8 gene mutants

FGFR3 encodes a member of the fibroblast growth factor receptor (FGFR) family

This gene encodes a threonine synthase-like protein

This protein also localizes to kinetochores of mitotic cells

Keratin 8 Polyclonal Antibody, 20ul Dry Bath A mutation in the mouseThis gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal

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