GNAO Polyclonal Antibody, 20ul Drug Development and Evaluation This gene encodes a large

This gene encodes a large protein that resides in the limiting membrane of endosomes and lysosomes and mediates intracellular cholesterol trafficking via binding of cholesterol to its N-terminal domain

This protein was shown to function as a water-selective channel

members of which have been identified in many animal species ranging from the nematode to human

The alpha and alpha' chains contain the catalytic site

GNAO Polyclonal Antibody, 20ul Drug Development and Evaluation This gene encodes a largeThe protein encoded by this gene represents the alpha subunit of the Go heterotrimeric G protein signal transducing complex. Defects in this gene are a cause of early onset epileptic encephalopathy. Two transcript variants encoding different isoforms have been found for this gene.