LIMK-2(Phospho Thr505) Polyclonal Antibody, 50ul Liquid Handling ＆Storage The gap junction protein alpha

The gap junction protein alpha 5 is a component of gap junctions

This protein is proteolytically cleaved into alpha and beta subunits that form a heterodimeric complex

but through transcription factors MEF2C and MEF2D

The C-terminus contains binding sites for proteins such as beta-1-integrin| actin| and vinculin

LIMK-2(Phospho Thr505) Polyclonal Antibody, 50ul Liquid Handling ＆Storage The gap junction protein alphaThere are approximately 40 known eukaryotic LIM proteins, so named for the LIM domains they contain. LIM domains are highly conserved cysteine rich structures containing 2 zinc fingers. Although zinc fingers usually function by binding to DNA or RNA, the LIM motif probably mediates protein protein interactions. LIM kinase 1 and LIM kinase 2 belong to a small subfamily with a unique combination of 2 N terminal LIM motifs and a C terminal protein kinase