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PLOD2 Polyclonal Antibody, 20ul Pathway and Network Analysis such as TRAF7

SKU: 25396341420

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PLOD2 Polyclonal Antibody, 20ul Pathway and Network Analysis such as TRAF7The protein encoded by this gene is a membrane bound homodimeric enzyme that is localized to the cisternae of the rough endoplasmic reticulum. The enzyme (cofactors iron and ascorbate) catalyzes the hydroxylation of lysyl residues in collagen like peptides. The resultant hydroxylysyl groups are attachment sites for carbohydrates in collagen and thus are critical for the stability of intermolecular crosslinks. Some patients with Ehlers Danlos syndrome

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Description

such as TRAF7

and DNA polymerase beta

Knockout studies in mice suggest that this gene plays a role in T-helper cell activation| and may be involved in inflammation and immune regulation

This gene encodes an enzyme which catalyzes the translocation of the Man(5)GlcNAc (2)-PP-Dol intermediate from the cytoplasmic to the luminal side of the endoplasmic reticulum membrane in the pathway for the N-glycosylation of proteins

PLOD2 Polyclonal Antibody, 20ul Pathway and Network Analysis such as TRAF7The protein encoded by this gene is a membrane bound homodimeric enzyme that is localized to the cisternae of the rough endoplasmic reticulum. The enzyme (cofactors iron and ascorbate) catalyzes the hydroxylation of lysyl residues in collagen like peptides. The resultant hydroxylysyl groups are attachment sites for carbohydrates in collagen and thus are critical for the stability of intermolecular crosslinks. Some patients with Ehlers Danlos syndrome

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