HMG-14 Polyclonal Antibody, 100ul Capsule Filter Germline mutations in this gene

Germline mutations in this gene may be associated with tumor predisposition syndrome (TPDS)

Phosphorylation of the encoded protein targets it for destruction by the ubiquitin pathway

This gene encodes one of the catalytic subunits of protein kinase A| which exists as a tetrameric holoenzyme with two regulatory subunits and two catalytic subunits| in its inactive form

The 5' untranslated region of this

HMG-14 Polyclonal Antibody, 100ul Capsule Filter Germline mutations in this geneThe high mobility group nucleosome binding domain 1 encoded by HMGN1 binds nucleosomal DNA and is associated with transcriptionally active chromatin. Along with a similar protein, HMG17, the encoded protein may help maintain an open chromatin configuration around transcribable genes.