AXIN1 Polyclonal Antibody, 100ul Hepatocytes and GP9 have been shown

and GP9 have been shown to cause Bernard-Soulier syndrome (MIM 231200)

Expression of this gene may play a role in the tumorigenesis and metastasis of several malignancies including breast cancer

Mutations in this gene cause a potentially fatal autoinflammatory syndrome in human patients

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AXIN1 Polyclonal Antibody, 100ul Hepatocytes and GP9 have been shownThis gene encodes a cytoplasmic protein which contains a regulation of G protein signaling (RGS) domain and a dishevelled and axin (DIX) domain. The encoded protein interacts with adenomatosis polyposis coli, catenin beta 1, glycogen synthase kinase 3 beta, protein phosphate 2, and itself. This protein functions as a negative regulator of the wingless type MMTV integration site family, member 1 (WNT) signaling pathway and can induce apoptosis. The