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Siah-1/2 Polyclonal Antibody, 100ul Protein Analysis The protein encoded by this

SKU: 25760905117

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SEK141.00 SEK181.00

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Siah-1/2 Polyclonal Antibody, 100ul Protein Analysis The protein encoded by thisSIAH1 encodes E3 ubiquitin protein ligase SIAH1 that is a member of the seven in absentia homolog (SIAH) family. The protein is an E3 ligase and is involved in ubiquitination and proteasome mediated degradation of specific proteins. The activity of this ubiquitin ligase has been implicated in the development of certain forms of Parkinson's disease, the regulation of the cellular response to hypoxia and induction of apoptosis. Alternative splicing

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Description

The protein encoded by this gene is the fifth subunit of GPI transamidase that attaches GPI-anchors to proteins

but it appears to be catalytically inactive

The protein encoded by this gene recognizes bacterial flagellin

Interactions between the Golgi and microtubules are thought to be important for the reorganization of the Golgi after it fragments during mitosis

Siah-1/2 Polyclonal Antibody, 100ul Protein Analysis The protein encoded by thisSIAH1 encodes E3 ubiquitin protein ligase SIAH1 that is a member of the seven in absentia homolog (SIAH) family. The protein is an E3 ligase and is involved in ubiquitination and proteasome mediated degradation of specific proteins. The activity of this ubiquitin ligase has been implicated in the development of certain forms of Parkinson's disease, the regulation of the cellular response to hypoxia and induction of apoptosis. Alternative splicing

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