Porcine Plasminogen Activator Inhibitor 1, PAI-1 ELISA Kit, 96T Filtration This gene originally was thought

This gene originally was thought to be located at 17q21

Impairs HCV replication via RNA editing at multiple sites

GO annotations related to this gene include G-protein coupled receptor activity and complement component C5a binding

promotes the synthesis and release of cytokines but impairs events leading to degranulation (PubMed: 2$458

Porcine Plasminogen Activator Inhibitor 1, PAI-1 ELISA Kit, 96T Filtration This gene originally was thoughtSerine protease inhibitor. Inhibits TMPRSS7. Is a primary inhibitor of tissue type plasminogen activator (PLAT) and urokinase type plasminogen activator (PLAU). As PLAT inhibitor, it is required for fibrinolysis down regulation and is responsible for the controlled degradation of blood clots. As PLAU inhibitor, it is involved in the regulation of cell adhesion and spreading. Acts as a regulator of cell migration, independently of its role as protease