PERK(Phospho Thr981) Polyclonal Antibody, 50ul Nucleic Acid Amplification This kinase mediates the signaling
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PERK(Phospho Thr981) Polyclonal Antibody, 50ul Nucleic Acid Amplification This kinase mediates the signalingThe protein encoded by this gene phosphorylates the alpha subunit of eukaryotic translation initiation factor 2, leading to its inactivation, and thus to a rapid reduction of translational initiation and repression of global protein synthesis. This protein is thought to modulate mitochondrial function. It is a type I membrane protein located in the endoplasmic reticulum (ER), where it is induced by ER stress caused by malfolded proteins. Mutations in
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