MC4-R Polyclonal Antibody, 100ul Centrifugal Filter The activated receptor kinase subsequently

The activated receptor kinase subsequently phosphorylates and activates multiple cytoplasmic effector molecules in pathways involved in apoptosis

does not produce GMP (PubMed: 20180847)

May have a role in activation-induced cell death or differentiation of T-cells

It also plays a role in clustering of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA)-type glutamate receptors at established synapses

MC4-R Polyclonal Antibody, 100ul Centrifugal Filter The activated receptor kinase subsequentlyThe protein encoded by MC4R is a membrane bound receptor and member of the melanocortin receptor family. The encoded protein interacts with adrenocorticotropic and MSH hormones and is mediated by G proteins. This is an intronless gene. Defects in this gene are a cause of autosomal dominant obesity.