Rat Inhibitor of Nuclear Factor Kappa-B Kinase Subunit Beta, IKBKB ELISA Kit, 96T Gene Synthesis AGFG2 is a member of

AGFG2 is a member of the HIV-1 Rev binding protein (HRB) family and encodes a protein with one Arf-GAP zinc finger domain

This inhibitor appears to be species-specific

a process required for the histone to proamine transition in spermatogenesis

Also induces the retraction of MVECs lamellipodia and filopodia in a ROCK pathway-dependent manner (PubMed: 23625008)

Rat Inhibitor of Nuclear Factor Kappa-B Kinase Subunit Beta, IKBKB ELISA Kit, 96T Gene Synthesis AGFG2 is a member ofSerine kinase that plays an essential role in the NF kappa B signaling pathway which is activated by multiple stimuli such as inflammatory cytokines, bacterial or viral products, DNA damages or other cellular stresses. Acts as part of the canonical IKK complex in the conventional pathway of NF kappa B activation and phosphorylates inhibitors of NF kappa B on 2 critical serine residues. These modifications allow polyubiquitination of the inhibitors and