Human Calretinin, CR ELISA Kit, 96T Gel & Buffers This protein binds to the

This protein binds to the SH3 domains of GRB2| an adaptor protein that couples tyrosine kinase receptors to SOS (a guanine nucleotide exchange factor for Ras)| via its C-terminal proline-rich sequences| and may thus modulate growth factor/Ras pathways by competing with SOS for binding to GRB2

The protein encoded by this gene is a preproprotein that is proteolytically processed to form the secreted opioid peptides beta-neoendorphin

and sequester them in the nucleolus

and as a positive regulator by preventing the processing of GLI3 into its repressor form

Human Calretinin, CR ELISA Kit, 96T Gel & Buffers This protein binds to the