MCP Polyclonal Antibody, 100ul Endonucleases & Exonucleases Defects in this gene are

Defects in this gene are a cause of Niemann-Pick disease type A (NPA) and Niemann-Pick disease type B (NPB)

HIST1H1B is found in the small histone gene cluster on chromosome 6p22-p21

subcellular location:Associated with perinuclear vesicles

Contains 1 pseudo-CRIB domain

MCP Polyclonal Antibody, 100ul Endonucleases & Exonucleases Defects in this gene areThe protein encoded by this gene is a type I membrane protein and is a regulatory part of the complement system. The encoded protein has cofactor activity for inactivation of complement components C3b and C4b by serum factor I, which protects the host cell from damage by complement. In addition, the encoded protein can act as a receptor for the Edmonston strain of measles virus, human herpesvirus 6, and type IV pili of pathogenic Neisseria. Finally,