NEIL1 Polyclonal Antibody, 100ul Microplate Mixer Inhibition of the encoded protein

Inhibition of the encoded protein restores hemostasis in animal models of hemophilia

Alternative splicing

as well as usage of alternative AUG and non-AUG translation initiation codons

Activity can be restored to the latent form of PAI-1 through denaturation and renaturation

NEIL1 Polyclonal Antibody, 100ul Microplate Mixer Inhibition of the encoded proteinNEIL1 is a member of the Nei endonuclease VIII like gene family which encodes DNA glycosylases. The encoded enzyme participates in the DNA repair pathway by initiating base excision repair by removing damaged bases, primarily oxidized pyrimidines. Multiple transcript variants encoding different isoforms have been found for this gene.