REPS1(Phospho-Ser709) Rabbit Polyclonal Antibody, 20ul Peptide Modification 3 nuclear translocation signals (NLSs)

3 nuclear translocation signals (NLSs)

The protein encoded by DOK2 (docking protein 2)is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase

including RNA polymerase II transcription

and mediates activation of the RET tyrosine kinase receptor

REPS1(Phospho-Ser709) Rabbit Polyclonal Antibody, 20ul Peptide Modification 3 nuclear translocation signals (NLSs)This gene encodes a signaling adaptor protein with two EH domains that interacts with proteins that participate in signaling endocytosis and cytoskeletal changes. The encoded protein has been found in association with intersectin 1 and Src homology 3 domain growth factor receptor bound 2 like (endophilin) interacting protein 1 when intersectin 1 was isolated from clathrin coated pits. The encoded protein has also been shown to interact with