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Neu Polyclonal Antibody, 20ul[BT-AP05904] Protein Expression Multiple alternatively spliced transcript variants

SKU: 2768745577

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SEK97.20 SEK123.20

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Neu Polyclonal Antibody, 20ul[BT-AP05904] Protein Expression Multiple alternatively spliced transcript variantsERBB2 encodes a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases. Receptor tyrosine protein kinase erbB 2 has no ligand binding domain of its own and therefore cannot bind growth factors. However, it does bind tightly to other ligand bound EGF receptor family members to form a heterodimer, stabilizing ligand binding and enhancing kinase mediated activation of downstream signalling pathways, such as those

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Description

Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene

ART1 (ADP-ribosyltransferase 1) was previously designated ART2

Two transcript variants encoding different isoforms have been found for MRPL22

which results in a fusion gene that is present in the majority of Ewing sarcoma cases

Neu Polyclonal Antibody, 20ul[BT-AP05904] Protein Expression Multiple alternatively spliced transcript variantsERBB2 encodes a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases. Receptor tyrosine protein kinase erbB 2 has no ligand binding domain of its own and therefore cannot bind growth factors. However, it does bind tightly to other ligand bound EGF receptor family members to form a heterodimer, stabilizing ligand binding and enhancing kinase mediated activation of downstream signalling pathways, such as those

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