CARP Polyclonal Antibody, 50ul Cell Culture Flasks PRKD1 is a serine/threonine kinase

PRKD1 is a serine/threonine kinase that regulates a variety of cellular functions

This gene's protein product is postulated to protect mitochondria against lipid-induced oxidative stress

and studies in rat suggest that alternative use of the two translation initiation sites results in N-terminally distinct protein isoforms with different subcellular localization

Isoform 1 and isoform 2 interact with CUL5 but not with CUL1

CARP Polyclonal Antibody, 50ul Cell Culture Flasks PRKD1 is a serine/threonine kinaseThe protein (ankyrin repeat domain 1) encoded by ANKRD1 is localized to the nucleus of endothelial cells and is induced by IL 1 and TNF alpha stimulation. Studies in rat cardiomyocytes suggest that ANKRD1 functions as a transcription factor. Interactions between this protein and the sarcomeric proteins myopalladin and titin suggest that it may also be involved in the myofibrillar stretch sensor system.