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SSRG Polyclonal Antibody, 50ul Peptide Library is a 71 amino acid

SKU: 28448603052

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PLN162.00 PLN198.00

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SSRG Polyclonal Antibody, 50ul Peptide Library is a 71 amino acidThe signal sequence receptor (SSR) is a glycosylated endoplasmic reticulum (ER) membrane receptor associated with protein translocation across the ER membrane. The SSR is comprised of four membrane proteins subunits: alpha, beta, gamma, and delta. The first two are glycosylated subunits and the latter two are non glycosylated subunits. This gene encodes the gamma subunit, which is predicted to span the membrane four times.

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Description

is a 71 amino acid protein that contains one helicase ATP-binding domain and one helicase C-terminal domain

This gene contains stretches of trinucleotide repeats and is located in the chromosome 22 region which is deleted in DiGeorge syndrome

It is expressed at low levels in the cytoplasm of pro-B and pre-B cells and present on the cell surface only at mature stages of B-cell differentiation

Expansion of a 20 amino acid polyalanine tract in this protein by 5-13 aa has been associated with congenital central hypoventilation syndrome

SSRG Polyclonal Antibody, 50ul Peptide Library is a 71 amino acidThe signal sequence receptor (SSR) is a glycosylated endoplasmic reticulum (ER) membrane receptor associated with protein translocation across the ER membrane. The SSR is comprised of four membrane proteins subunits: alpha, beta, gamma, and delta. The first two are glycosylated subunits and the latter two are non glycosylated subunits. This gene encodes the gamma subunit, which is predicted to span the membrane four times.

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