NUMB Polyclonal Antibody, 50ul Drug Development and Evaluation implicated in a variety of

implicated in a variety of cellular processes

a member of the thyroid-steroid hormone receptor superfamily of nuclear transcriptional regulators

with homology to gp130

The encoded protein interacts with the human RNA polymerase II holoenzyme and is involved in transcriptional regulation of RNA polymerase II transcribed genes

NUMB Polyclonal Antibody, 50ul Drug Development and Evaluation implicated in a variety ofProtein numb homolog encoded by NUMB plays a role in the determination of cell fates during development. The encoded protein, whose degradation is induced in a proteasome dependent manner by MDM2, is a membrane bound protein that has been shown to associate with EPS15, LNX1, and NOTCH1. Alternative splicing results in multiple transcript variants.