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PTEN mouse Monoclonal Antibody(2C10), 50ul Antibody Humanization glycosylphosphatidylinositol-anchored protein of 181 amino

SKU: 29184131617

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PTEN mouse Monoclonal Antibody(2C10), 50ul Antibody Humanization glycosylphosphatidylinositol-anchored protein of 181 aminoThis gene was identified as a tumor suppressor that is mutated in a large number of cancers at high frequency. The protein encoded by this gene is a phosphatidylinositol 3,4,5 trisphosphate 3 phosphatase. It contains a tensin like domain as well as a catalytic domain similar to that of the dual specificity protein tyrosine phosphatases. Unlike most of the protein tyrosine phosphatases, this protein preferentially dephosphorylates phosphoinositide

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Description

glycosylphosphatidylinositol-anchored protein of 181 amino acids with a single Ig-like domain weakly homologous to KIR2DL4 molecule

Mutations in this gene have been associated with Pfeiffer syndrome

|disease:A chromosomal aberration involving NFKB2 is found in a cutaneous T-cell leukemia (C-TCL) cell line

are membrane-bound proteins with long N termini containing multiple domains

PTEN mouse Monoclonal Antibody(2C10), 50ul Antibody Humanization glycosylphosphatidylinositol-anchored protein of 181 aminoThis gene was identified as a tumor suppressor that is mutated in a large number of cancers at high frequency. The protein encoded by this gene is a phosphatidylinositol 3,4,5 trisphosphate 3 phosphatase. It contains a tensin like domain as well as a catalytic domain similar to that of the dual specificity protein tyrosine phosphatases. Unlike most of the protein tyrosine phosphatases, this protein preferentially dephosphorylates phosphoinositide

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