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Rb Polyclonal Antibody, 50ul[BT-AP07687] Cytokines generally promoting their degradation by

SKU: 29310407390

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Rb Polyclonal Antibody, 50ul[BT-AP07687] Cytokines generally promoting their degradation byThe protein encoded by RB1 (RB transcriptional corepressor 1) is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in RB1 are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

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Description

generally promoting their degradation by the proteasome

whose members play a key role in the regulation of actin cytoskeleton organization in response to extracellular growth factors

BAI1 contains at least one 'functional' p53-binding site within an intron

This gene is a member of the guanine nucleotide-binding protein (G protein) gamma family and encodes a lipid-anchored| cell membrane protein

Rb Polyclonal Antibody, 50ul[BT-AP07687] Cytokines generally promoting their degradation byThe protein encoded by RB1 (RB transcriptional corepressor 1) is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in RB1 are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

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