ASB3 Rabbit Polyclonal Antibody, 50ul Mechanical Pipette Members of the CNN gene

Members of the CNN gene family all contain similar tandemly repeated motifs

This interaction is inversely correlated to the length of the polyglutamine tract added to the huntingtin protein in Huntington disease

Additional transcript variants have been described but their full-length nature is not known

This protein is located in the nucleus and must dimerize with another bHLH protein in order to bind DNA

ASB3 Rabbit Polyclonal Antibody, 50ul Mechanical Pipette Members of the CNN geneThe protein encoded by this gene is a member of the ankyrin repeat and SOCS box containing (ASB) family of proteins. They contain ankyrin repeat sequence and SOCS box domain. The SOCS box serves to couple suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation. Alternatively spliced transcript variants have been described for this gene.