Raf-1(Phospho Thr269) Polyclonal Antibody, 50ul Hybridoma Antibody Sequencing This protein is a target

This protein is a target for SMAD-specific E3 ubiquitin ligases

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through which this receptor induces the activation of NF-kappa B and MAPK8/JNK

Raf-1(Phospho Thr269) Polyclonal Antibody, 50ul Hybridoma Antibody Sequencing This protein is a targetThis gene is the cellular homolog of viral raf gene (v raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated, the cellular RAF1 protein can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2, which in turn phosphorylate to activate the serine threonine specific protein kinases, ERK1 and ERK2.