Mdm2 Polyclonal Antibody, 50ul[BT-AP05302] Peptide Synthesis While the interaction with CBL

While the interaction with CBL is apparently mediated via the hydrophobic region of this domain

The encoded protein can also modulate signaling of other melanocortin receptors

The protein encoded by this gene is a high affinity calcium ion-binding protein that is structurally and functionally similar to calmodulin and troponin C

This gene encodes a member of a family of proteins that are receptor associated proteins of the synapse

Mdm2 Polyclonal Antibody, 50ul[BT-AP05302] Peptide Synthesis While the interaction with CBLMDM2 encodes a nuclear localized E3 ubiquitin ligase. E3 ubiquitin protein ligase Mdm2 can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. MDM2 is itself transcriptionally regulated by p53. Overexpression or amplification of this locus is detected in a variety of different cancers. There is a pseudogene for this gene on chromosome 2. Alternative splicing results in a multitude of transcript