SARM1 Polyclonal Antibody, 20ul Pasteur Pipets Tumor necrosis factor receptor superfamily

Tumor necrosis factor receptor superfamily member 3 plays a role in signalling during the development of lymphoid and other organs

Autoantibodies targeting the encoded protein may be a diagnostic marker for endometriosis

and its activity is mediated by adenylate cyclase

Mutations in THRB are known to be a cause of generalized thyroid hormone resistance (GTHR)

SARM1 Polyclonal Antibody, 20ul Pasteur Pipets Tumor necrosis factor receptor superfamilyWas initially reported to contain ARM repeats (PubMed: 11386760). Such repeats are however not predicted by any detection method.,Involved in innate immnune response. Acts as a negative regulator of TICAM1 TRIF dependent Toll like receptor signaling by inhibiting induction of TLR3 and TLR4 dependent genes. Specifically blocks TICAM1 TRIF dependent transcription factor activation and gene induction, without affecting the MYD88 dependent pathway or non