ATR Polyclonal Antibody, 50ul Centrifuges The protein is nuclear in

The protein is nuclear in the M and G1 phases of the cell cycle and moves to the cytoplasm during S and G2

Several alternatively spliced transcripts have been observed that contain disrupted coding regions and likely encode nonfunctional proteins

Defects in this gene are a cause of chromosome 9q subtelomeric deletion syndrome (9q-syndrome

Contactins are axon-associated cell adhesion molecules that function in neuronal network formation and plasticity

ATR Polyclonal Antibody, 50ul Centrifuges The protein is nuclear inThe protein encoded by ATR (ATR serine threonine kinase) belongs the PI3 PI4 kinase family, and is most closely related to ATM, a protein kinase encoded by the gene mutated in ataxia telangiectasia. This protein and ATM share similarity with Schizosaccharomyces pombe rad3, a cell cycle checkpoint gene required for cell cycle arrest and DNA damage repair in response to DNA damage. This kinase has been shown to phosphorylate checkpoint kinase CHK1,