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Phospho-APC (S2054) Polyclonal Antibody, 100ul Cell Function Analysis The type I isoform encoded

SKU: 3157669336

4.1
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Phospho-APC (S2054) Polyclonal Antibody, 100ul Cell Function Analysis The type I isoform encodedAPC encodes a tumor suppressor protein that acts as an antagonist of the Wnt signaling pathway. It is also involved in other processes including cell migration and adhesion, transcriptional activation, and apoptosis. Defects in this gene cause familial adenomatous polyposis (FAP), an autosomal dominant pre malignant disease that usually progresses to malignancy. Disease associated mutations tend to be clustered in a small region designated the

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Description

The type I isoform encoded by ARG1

a dimerization domain

This protein may also play a role in oncogenesis

possibly as a result of compromised regulatory T cell recruitment

Phospho-APC (S2054) Polyclonal Antibody, 100ul Cell Function Analysis The type I isoform encodedAPC encodes a tumor suppressor protein that acts as an antagonist of the Wnt signaling pathway. It is also involved in other processes including cell migration and adhesion, transcriptional activation, and apoptosis. Defects in this gene cause familial adenomatous polyposis (FAP), an autosomal dominant pre malignant disease that usually progresses to malignancy. Disease associated mutations tend to be clustered in a small region designated the

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