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Prothrombin Polyclonal Antibody, 100ul[BT-AP07416] Enzyme-Linked Immunosorbent Assay (ELISA) This protein transports low-density lipoproteins

SKU: 3237808340

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Prothrombin Polyclonal Antibody, 100ul[BT-AP07416] Enzyme-Linked Immunosorbent Assay (ELISA) This protein transports low-density lipoproteinsCoagulation factor II is proteolytically cleaved to form thrombin in the first step of the coagulation cascade which ultimately results in the stemming of blood loss. F2 also plays a role in maintaining vascular integrity during development and postnatal life. Peptides derived from the C terminus of this protein have antimicrobial activity against E. coli and P. aeruginosa. Mutations in F2 lead to various forms of thrombosis and dysprothrombinemia.

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Description

This protein transports low-density lipoproteins to late endosomal/lysosomal compartments where they are hydrolized and released as free cholesterol

The encoded protein acts as a transcriptional repressor that binds to E-box motifs and is also likely to repress E-cadherin transcription in breast carcinoma

upon stress to the ER

Decreased expression of this gene may be associated with tumor growth and metastasis

Prothrombin Polyclonal Antibody, 100ul[BT-AP07416] Enzyme-Linked Immunosorbent Assay (ELISA) This protein transports low-density lipoproteinsCoagulation factor II is proteolytically cleaved to form thrombin in the first step of the coagulation cascade which ultimately results in the stemming of blood loss. F2 also plays a role in maintaining vascular integrity during development and postnatal life. Peptides derived from the C terminus of this protein have antimicrobial activity against E. coli and P. aeruginosa. Mutations in F2 lead to various forms of thrombosis and dysprothrombinemia.

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