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MDMX Polyclonal Antibody, 100ul CellSafe™ It is located mainly in

SKU: 32475655664

4.5
EUR123.75 EUR168.75

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MDMX Polyclonal Antibody, 100ul CellSafe™ It is located mainly inMDM4 encodes a nuclear protein that contains a p53 binding domain at the N terminus and a RING finger domain at the C terminus, and shows structural similarity to p53 binding protein MDM2. Both proteins bind the p53 tumor suppressor protein and inhibit its activity, and have been shown to be overexpressed in a variety of human cancers. However, unlike MDM2 which degrades p53, this protein inhibits p53 by binding its transcriptional activation domain.

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Description

It is located mainly in dense fibrillar regions of the nucleolus

The gamma globin genes (HBG1 and HBG2) are normally expressed in the fetal liver| spleen and bone marrow

PDP2 is a mitochondrial protein that functions as a phosphatase and is involved in the enzymatic resetting of the pyruvate dehydrogenase complex

including interleukin 6

MDMX Polyclonal Antibody, 100ul CellSafe™ It is located mainly inMDM4 encodes a nuclear protein that contains a p53 binding domain at the N terminus and a RING finger domain at the C terminus, and shows structural similarity to p53 binding protein MDM2. Both proteins bind the p53 tumor suppressor protein and inhibit its activity, and have been shown to be overexpressed in a variety of human cancers. However, unlike MDM2 which degrades p53, this protein inhibits p53 by binding its transcriptional activation domain.

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