PIGR Polyclonal Antibody, 50ul Gloves its expression is upregulated in

its expression is upregulated in human osteoarthritic joint cartilage

can act as an estrogen receptor co-repressor and is a candidate for breast tumorigenesis

Alternative splicing results in transcript variants

Mutations in CBX2 are also associated with gonadal dysgenesis in humans

PIGR Polyclonal Antibody, 50ul Gloves its expression is upregulated inThis gene is a member of the immunoglobulin superfamily. The encoded poly Ig receptor binds polymeric immunoglobulin molecules at the basolateral surface of epithelial cells; the complex is then transported across the cell to be secreted at the apical surface. A significant association was found between immunoglobulin A nephropathy and several SNPs in this gene.