Nov Polyclonal Antibody, 50ul Recombinant Protein Expression Mutations in ADAMTS2 cause Ehlers-Danlos

Mutations in ADAMTS2 cause Ehlers-Danlos syndrome type VIIC

The encoded protein is required for completion of the mitotic cycle and for targeting protein phosphatase-1 to mitotic kinetochores

Mutations in TUBA1A cause lissencephaly type 3 (LIS3) - a neurological condition characterized by microcephaly

May promote the rapid formation of a branched actin network by first nucleating new mother filaments and then activating Arp2/3 to branch off these filaments

Nov Polyclonal Antibody, 50ul Recombinant Protein Expression Mutations in ADAMTS2 cause Ehlers-DanlosProtein NOV homolog encoded by NOV is a small secreted cysteine rich protein and a member of the CCN family of regulatory proteins. CNN family proteins associate with the extracellular matrix and play an important role in cardiovascular and skeletal development, fibrosis and cancer development.