TRY6 Rabbit Polyclonal Antibody, 50ul Glassware Sets This gene is located at

This gene is located at the pseudoautosomal regions of X and Y chromosomes

This is supported by studies in knockout mice showing development of soft-tissue sarcomas| ovarian stromal cell tumors and a high sensitivity to carcinogenic treatmen

Targeted to sites of DNA damage through interaction with poly(ADP-ribose) and functions to regulate chromatin during DNA repair

It is thought that this secreted protein contains antitumor activity

TRY6 Rabbit Polyclonal Antibody, 50ul Glassware Sets This gene is located atAlthough this locus appears to encode a protein similar to trypsinogen the locus is thought to be a transcribed pseudogene. ESTs support its transcription but expression of its predicted protein has not been observed. Its predicted protein sequence differs significantly from the known functional trypsinogens including a different amino acid at the conserved residue 122 which is important for autolysis. This pseudogene and several other trypsinogen