HMG-17 (Acetyl Lys3) Rabbit Polyclonal Antibody, 100ul Plates & Dishes Mutations or deletions in this

Mutations or deletions in this gene have been shown to result in pancreatic cancer

Diseases associated with GK2 include glycerol kinase deficiency and x-linked adrenal hypoplasia congenita

Alternatively spliced transcript variants that encode different isoforms by using the two downstream repeat units as splice donor sites have been described

This gene encodes a member the HERC ubiquitin ligase family

HMG-17 (Acetyl Lys3) Rabbit Polyclonal Antibody, 100ul Plates & Dishes Mutations or deletions in thisThe protein encoded by this gene binds nucleosomal DNA and is associated with transcriptionally active chromatin. Along with a similar protein HMGN1 the encoded protein may help maintain an open chromatin configuration around transcribable genes. The protein has also been found to have antimicrobial activity against bacteria viruses and fungi.