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DVL1 Polyclonal Antibody, 100ul Cellular Function Assays Isoforms that are expressed in

SKU: 34194817505

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DVL1 Polyclonal Antibody, 100ul Cellular Function Assays Isoforms that are expressed inDVL1, the human homolog of the Drosophila dishevelled gene (dsh) encodes a cytoplasmic phosphoprotein that regulates cell proliferation, acting as a transducer molecule for developmental processes, including segmentation and neuroblast specification. DVL1 is a candidate gene for neuroblastomatous transformation. The Schwartz Jampel syndrome and Charcot Marie Tooth disease type 2A have been mapped to the same region as DVL1. The phenotypes of these

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Description

Isoforms that are expressed in muscle and ubiquitously expressed isoforms localize to the cytoplasm and nucleus and activate a caspase-independent apoptotic process

This cytokine displays chemotactic activity for monocytes but not for lymphocytes

GO annotations related to this gene include G-protein coupled receptor activity andtransmembrane signaling receptor activity

The encoded protein plays a role in multiple aspects of mRNA maturation and is associated with several multiprotein complexes including the apoB RNA editing-complex and survival of motor neurons (SMN) complex

DVL1 Polyclonal Antibody, 100ul Cellular Function Assays Isoforms that are expressed inDVL1, the human homolog of the Drosophila dishevelled gene (dsh) encodes a cytoplasmic phosphoprotein that regulates cell proliferation, acting as a transducer molecule for developmental processes, including segmentation and neuroblast specification. DVL1 is a candidate gene for neuroblastomatous transformation. The Schwartz Jampel syndrome and Charcot Marie Tooth disease type 2A have been mapped to the same region as DVL1. The phenotypes of these

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