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TTF-1 Polyclonal Antibody, 50ul Polyclonal Antibody Preparation 2002 [PubMed 11784320])

SKU: 34307441151

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SEK162.00 SEK201.00

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TTF-1 Polyclonal Antibody, 50ul Polyclonal Antibody Preparation 2002 [PubMed 11784320])NKX2 1 (NK2 homeobox 1) encodes a protein initially identified as a thyroid specific transcription factor. The encoded protein binds to the thyroglobulin promoter and regulates the expression of thyroid specific genes but has also been shown to regulate the expression of genes involved in morphogenesis. Mutations and deletions in NKX2 1 are associated with benign hereditary chorea, choreoathetosis, congenital hypothyroidism, and neonatal respiratory

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Description

2002 [PubMed 11784320])

It is a type I integral membrane protein with a heavily glycosylated extracellular domain and binds to tissue- and organ-specific lectins or selectins

tissue specificity:Brain specific mainly in the limbic system and faintly in the spinal cord but not in cerebellum

cells from all PBD patients exhibit a defect in the import of one or more classes of peroxisomal matrix proteins into the organelle

TTF-1 Polyclonal Antibody, 50ul Polyclonal Antibody Preparation 2002 [PubMed 11784320])NKX2 1 (NK2 homeobox 1) encodes a protein initially identified as a thyroid specific transcription factor. The encoded protein binds to the thyroglobulin promoter and regulates the expression of thyroid specific genes but has also been shown to regulate the expression of genes involved in morphogenesis. Mutations and deletions in NKX2 1 are associated with benign hereditary chorea, choreoathetosis, congenital hypothyroidism, and neonatal respiratory

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