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Tuberin Polyclonal Antibody, 50ul[BT-AP09286] Protein Research RPS6KA2 (ribosomal protein S6 kinase

SKU: 34342006833

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Tuberin Polyclonal Antibody, 50ul[BT-AP09286] Protein Research RPS6KA2 (ribosomal protein S6 kinaseMutations in TSC2 (tuberous sclerosis 2) lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin. Alternative splicing results in multiple transcript variants encoding different isoforms.

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Description

RPS6KA2 (ribosomal protein S6 kinase A2) encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases

Interacts with RNF43

Mutations at this locus have been linked to autosomal recessive deafness

5)-trisphosphate and inositol-1

Tuberin Polyclonal Antibody, 50ul[BT-AP09286] Protein Research RPS6KA2 (ribosomal protein S6 kinaseMutations in TSC2 (tuberous sclerosis 2) lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin. Alternative splicing results in multiple transcript variants encoding different isoforms.

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