p53 Polyclonal Antibody, 50ul[BT-AP06814] Hepatocytes This gene is clustered with

This gene is clustered with other MAGED genes on chromosome Xp11

2001 [PubMed 11242035])

and may also function as tumor suppressors

Transcription factor E2F4 encoded by E2F4 is a member of the E2F family of transcription factors

p53 Polyclonal Antibody, 50ul[BT-AP06814] Hepatocytes This gene is clustered withTP53 (tumor protein p53) encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in TP53 are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni