Mouse Glycogen Synthase Kinase-3 Beta, GSK3B ELISA Kit, 96T Purification Binding to U3 small nucleolar

Binding to U3 small nucleolar RNA

This protein is activated by PI3-kinase

The expression of this gene is reported to be downregulated in colorectal carcinoma tissue suggesting that it is a candidate tumor suppressor gene

Alternatively spliced transcript variants encoding different protein isoforms have been described

Mouse Glycogen Synthase Kinase-3 Beta, GSK3B ELISA Kit, 96T Purification Binding to U3 small nucleolarConstitutively active protein kinase that acts as a negative regulator in the hormonal control of glucose homeostasis, Wnt signaling and regulation of transcription factors and microtubules, by phosphorylating and inactivating glycogen Synthase (GYS1 or GYS2), EIF2B, CTNNB1 beta catenin, APC, AXIN1, DPYSL2 CRMP2, JUN, NFATC1 NFATC, MAPT TAU and MACF1. Requires primed phosphorylation of the majority of its substrates. In skeletal muscle, contributes to