EAAT2 Polyclonal Antibody, 50ul Vacuum Aspirator This gene encodes a secreted

This gene encodes a secreted protein that dorsalizes early vertebrate embryonic tissues by binding to ventralizing TGF-beta-like bone morphogenetic proteins and sequestering them in latent complexes

The protein encoded by this gene contains a PDZ domain and a LIM domain| indicating that it may be involved in cytoskeletal assembly

A similar protein in mouse is required for proper brain and sensory organ development and can cause epilepsy

which are microtubule-based structures thought to help organize centrosomes

EAAT2 Polyclonal Antibody, 50ul Vacuum Aspirator This gene encodes a secretedThis gene encodes a member of a family of solute transporter proteins. The membrane bound protein is the principal transporter that clears the excitatory neurotransmitter glutamate from the extracellular space at synapses in the central nervous system. Glutamate clearance is necessary for proper synaptic activation and to prevent neuronal damage from excessive activation of glutamate receptors. Mutations in and decreased expression of this protein are