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Histone H2A.Z (Acetyl Lys12) Rabbit Polyclonal Antibody, 50ul PCR Series alpha-type (shown here) and beta-type

SKU: 37099679100

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Histone H2A.Z (Acetyl Lys12) Rabbit Polyclonal Antibody, 50ul PCR Series alpha-type (shown here) and beta-typeVariant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation DNA repair DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post translational modifications of histones also called histone

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Description

alpha-type (shown here) and beta-type (AC Q9HDB5)

a region with homology to SMC chromosome segregation ATPases

A related pseudogene has been found on chromosome 6

Regulation of gene expression in B lymphocytes by Aiolos is complex as it appears to require the sequential formation of Ikaros homodimers

Histone H2A.Z (Acetyl Lys12) Rabbit Polyclonal Antibody, 50ul PCR Series alpha-type (shown here) and beta-typeVariant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation DNA repair DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post translational modifications of histones also called histone

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