TFIIIC102 Polyclonal Antibody, 20ul Site-directed Mutagenesis Mutations in NBN are associated

Mutations in NBN are associated with Nijmegen breakage syndrome

DNA helicase which plays a role in chromatin-remodeling following DNA damage

The protein encoded by ATP5G2 is one of three precursors of subunit c

Translocations between this gene on chromosome 7 and the gene fused in sarcoma on chromosome 16 can be found in some tumors

TFIIIC102 Polyclonal Antibody, 20ul Site-directed Mutagenesis Mutations in NBN are associatedGeneral transcription factor 3C polypeptide 3 encoded by GTF3C3 is part of the TFIIIC2 complex, which binds to the promoters of small nuclear and cytoplasmic RNA genes in order to recruit RNA polymerase III. The TFIIIC2 complex is composed of six subunits. Two transcript variants encoding different isoforms have been found for this gene.