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Cdc25A(Phospho Thr507) Polyclonal Antibody, 50ul Centrifugal Filter The tumor necrosis factor superfamily

SKU: 37589861512

4.0
USD162.00 USD200.00

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Cdc25A(Phospho Thr507) Polyclonal Antibody, 50ul Centrifugal Filter The tumor necrosis factor superfamilyCDC25A is a member of the CDC25 family of phosphatases. CDC25A is required for progression from G1 to the S phase of the cell cycle. It activates the cyclin dependent kinase CDC2 by removing two phosphate groups. CDC25A is specifically degraded in response to DNA damage, which prevents cells with chromosomal abnormalities from progressing through cell division. CDC25A is an oncogene, although its exact role in oncogenesis has not been demonstrated.

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Description

The tumor necrosis factor superfamily member 4 functions in T cell antigen-presenting cell (APC) interactions and mediates adhesion of activated T cells to endothelial cells

and binds to other proteins containing glutamine-rich regions

Mutations in this gene have been associated with colorectal and gastric carcinomas

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Cdc25A(Phospho Thr507) Polyclonal Antibody, 50ul Centrifugal Filter The tumor necrosis factor superfamilyCDC25A is a member of the CDC25 family of phosphatases. CDC25A is required for progression from G1 to the S phase of the cell cycle. It activates the cyclin dependent kinase CDC2 by removing two phosphate groups. CDC25A is specifically degraded in response to DNA damage, which prevents cells with chromosomal abnormalities from progressing through cell division. CDC25A is an oncogene, although its exact role in oncogenesis has not been demonstrated.

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