p53 (Acetyl Lys372) Polyclonal Antibody, 100ul Digital Burette The preservation of the ORF

The preservation of the ORF by purifying selection in all Old World monkeys carrying it suggests that this locus is likely to be functional| possibly during male meiosis when X chromosomal genes are silenced or during haploid stages of spermatogenesis

Aspiration speed up to 1

and antiviral activity during viral infections

The encoded protein has been shown to be overexpressed in lung squamous cell carcinoma (PMID: 18057535) and regulated by p53 (PMID: 19602589)

p53 (Acetyl Lys372) Polyclonal Antibody, 100ul Digital Burette The preservation of the ORFTP53 encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. Tumor protein p53 responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in TP53 are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni syndrome. Alternative