BID (Cleaved-Arg71) Rabbit Polyclonal Antibody, 100ul Stepper resulting in up to four
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BID (Cleaved-Arg71) Rabbit Polyclonal Antibody, 100ul Stepper resulting in up to fourIntact BH3 motif is required by BIK BID BAK BAD and BAX for their pro apoptotic activity and for their interaction with anti apoptotic members of the Bcl 2 family. The major proteolytic product p15 BID allows the release of cytochrome c (By similarity). Isoform 1 isoform 2 and isoform 4 induce ICE like proteases and apoptosis. Isoform 3 does not induce apoptosis. Counters the protective effect of Bcl 2. PTM: Phosphorylated upon DNA damage probably by
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