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Otubain-1 Polyclonal Antibody, 100ul High Speed Micro-Centrifuges HNRNPK belongs to the subfamily

SKU: 37830212343

4.8
PLN141.00 PLN188.00

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Otubain-1 Polyclonal Antibody, 100ul High Speed Micro-Centrifuges HNRNPK belongs to the subfamilyThe product of OTUB1 (OTU deubiquitinase, ubiquitin aldehyde binding 1) is a member of the OTU (ovarian tumor) superfamily of predicted cysteine proteases. The encoded protein is a highly specific ubiquitin iso peptidase, and cleaves ubiquitin from branched poly ubiquitin chains but not from ubiquitinated substrates. It interacts with another ubiquitin protease and an E3 ubiquitin ligase that inhibits cytokine gene transcription in the immune system.

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Description

HNRNPK belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs)

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The gene product is recognized by IgG antibody isolated from a breast cancer patient and appears to be a molecular marker associated with a broad range of human malignancies

The encoded protein also appears to be important for stem cell proliferation

Otubain-1 Polyclonal Antibody, 100ul High Speed Micro-Centrifuges HNRNPK belongs to the subfamilyThe product of OTUB1 (OTU deubiquitinase, ubiquitin aldehyde binding 1) is a member of the OTU (ovarian tumor) superfamily of predicted cysteine proteases. The encoded protein is a highly specific ubiquitin iso peptidase, and cleaves ubiquitin from branched poly ubiquitin chains but not from ubiquitinated substrates. It interacts with another ubiquitin protease and an E3 ubiquitin ligase that inhibits cytokine gene transcription in the immune system.

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