PLEK2 Rabbit Polyclonal Antibody, 20ul Nucleic Acid Extraction miscellaneous:The N- and C-terminal domains

miscellaneous:The N- and C-terminal domains are separated by a 2-repeat G-Q region

It had previously been weakly linked to a syndrome known as Friedreich ataxia that has since been shown to be the result of mutation in a completely different gene

one encoding a secreted isoform and the others encoding nonsecreted isoforms

4-glycoside linkages

PLEK2 Rabbit Polyclonal Antibody, 20ul Nucleic Acid Extraction miscellaneous:The N- and C-terminal domainsThe protein encoded by this gene associates with membrane bound phosphatidylinositols generated by phosphatidylinositol 3 kinase. The encoded protein then interacts with the actin cytoskeleton to induce cell spreading. In conjunction with complement component 1 q subcomponent B chain (C1QB) this gene shows an increase in expression in melanoma cells and may serve as an accurate biomarker for the disease.